Click here to watch a short video describing some of our latest research efforts!
Overcoming resistance to AR-targeted therapy in metastatic, castration-resistant prostate cancer
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Developing immunocompetent mouse models of human prostate cancer with the ability to metastasize to clinically relevant locations
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Recent publications:
- Budreika A, Phoenix JT, Kostlan RJ, Deegan CD, Ferrari MG, Young KS, Fanning SW, & Kregel S (2025); The Homeobox Transcription Factor NKX3.1 Displays an Oncogenic Role in Castration-Resistant Prostate Cancer Cells. Cancers. Full Article
- Kostlan RJ, Phoenix JT, Budreika A, Ferrari MG, Khurana N, Choi JE, Juckette K, Mahapatra S, McCollum BL, Moskal R, Mannan R, Qiao Y, Vander Griend DJ, Chinnaiyan AM, and Kregel S (2024); Clinically Relevant Humanized Mouse Models of Metastatic Prostate Cancer Facilitate Therapeutic Evaluation. Mol Cancer Res. Full article
- Phoenix JT, Budreika A, Kostlan RJ, Hwang JH, Fanning SW and Kregel S (2023); Editorial: Hormone resistance in cancer. Front. Endocrinol. Full article